How do we know that Science is true?

How do we know that Science is true? How do we know that it I not merely true because culture says that it is true? How can anyone know what is true or false? How do you know that Science is not merely what culture makes of it? I am not anti-science! I am pro-truth! But what is true? What is false? Can science ever prove anything? Not all cultures acknowledge science! Don't those cultures count?